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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EYA1 All Species: 6.67
Human Site: Y94 Identified Species: 20.95
UniProt: Q99502 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q99502 NP_000494.2 592 64593 Y94 I Y P S N R P Y P H I L P T P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_849806 585 63912 T98 P Y P H I L P T P S S Q T M A
Cat Felis silvestris
Mouse Mus musculus P97767 591 64343 P94 I Y P S K S Y P H I L P T P S
Rat Rattus norvegicus XP_002729501 587 63925 Y94 I Y P S N R P Y P H I L P T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506770 633 68678 Q135 S A H Q Y S P Q L Y P S K P Y
Chicken Gallus gallus
Frog Xenopus laevis NP_001083888 592 64622 P94 Y P S N R A Y P H I L P T P S
Zebra Danio Brachydanio rerio NP_571268 609 66497 S111 F S P Q I Y P S N R A Y P H I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q05201 766 80638 K265 A A A V Y D G K H D Y Y Y Y N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 97.3 N.A. 94.9 96.1 N.A. 69.5 N.A. 92.5 85.5 N.A. 38.7 N.A. N.A. N.A.
Protein Similarity: 100 N.A. N.A. 97.8 N.A. 97.4 97.4 N.A. 79.1 N.A. 96.1 91.4 N.A. 51.7 N.A. N.A. N.A.
P-Site Identity: 100 N.A. N.A. 26.6 N.A. 26.6 100 N.A. 6.6 N.A. 0 20 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 33.3 100 N.A. 13.3 N.A. 13.3 20 N.A. 0 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 25 13 0 0 13 0 0 0 0 13 0 0 0 13 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 0 0 0 13 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % G
% His: 0 0 13 13 0 0 0 0 38 25 0 0 0 13 0 % H
% Ile: 38 0 0 0 25 0 0 0 0 25 25 0 0 0 13 % I
% Lys: 0 0 0 0 13 0 0 13 0 0 0 0 13 0 0 % K
% Leu: 0 0 0 0 0 13 0 0 13 0 25 25 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 13 0 % M
% Asn: 0 0 0 13 25 0 0 0 13 0 0 0 0 0 13 % N
% Pro: 13 13 63 0 0 0 63 25 38 0 13 25 38 38 25 % P
% Gln: 0 0 0 25 0 0 0 13 0 0 0 13 0 0 0 % Q
% Arg: 0 0 0 0 13 25 0 0 0 13 0 0 0 0 0 % R
% Ser: 13 13 13 38 0 25 0 13 0 13 13 13 0 0 25 % S
% Thr: 0 0 0 0 0 0 0 13 0 0 0 0 38 25 0 % T
% Val: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 13 50 0 0 25 13 25 25 0 13 13 25 13 13 13 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _